Tetanus Toxoid IgG




Test Mnemonic

TETAN

CPT Codes

  • 86317 - QTY (1)

LOINC ®

6367-7

Aliases

  • Anti-tetanus toxoid IgG
  • C. tetani
  • Clostridium tetani
  • Tetanus Immune Response
  • Tetanus toxoid antibodies
  • Tetanus toxoid antibodies

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) RefrigeratedSeparate serum from cells ASAP or within 2 hours of collection. 'Pre' and 'post' vaccine specimens may be submitted separately or together and post specimens must be received within 60 days from receipt of the pre specimens. Label specimens plainly as 'pre-vaccine' and 'post-vaccine.'

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.2 mL     

Stability

Environmental Condition Description
AmbientAfter separation from cells: 48 hours
RefrigeratedAfter separation from cells: 2 weeks
FrozenAfter separation from cells: 1 year (Avoid repeated freeze/thaw cycles)

Days Performed

Sun - Sat

Turnaround Time

2 - 4 days

Methodology

Name Description
Quantitative Multiplex Bead Assay 

Reference Range

Tetanus IgG Abs
Sex Age From Age To Type Range Range Unit
       > 0.1 IU/mL is usually considered protective 

Special Info

'Pre' and 'post' vaccine specimens can be submitted separately or together for testing; if shipped separately, post specimen must be received within 60 days of pre specimen. Mark specimens plainly as 'pre-vaccine" or 'post-vaccine'. This test is New York DOH approved.

Clinical Info

Responder status is determined according to the ratio of a one-month post-vaccination sample to pre-vaccination concentration of tetanus IgG antibodies as follows: (1) If the post-vaccination concentration is <1.0 IU, the patient is considered to be a nonresponder. (2) If the post-vaccination is greater that or equal to 1.0 IU, a patient with a ratio of less than 1.5 is a nonresponder, a ratio of 1.5 to <3.0, a weak responder, and a ratio of 3.0 or greater, a good responder. (3) If the pre-vaccination concentration is >1.0, it may be difficult to assess the response based on a ratio alone. A post-vaccination >2.5 IU in this case is usually adequate.