- 80338 / G0480 - QTY (1)
- Trazodone Serum/Plasma
|No additive (Red)
|Do not use serum separator tubes. Separate serum from cells within 2 hours of collection.
Alternate Specimen Requirements
|Separate plasma from cells within 2 hours of collection.
Minimum Specimen Requirements
|After separation from cells: 24 hours
|After separation from cells: 2 weeks
|After separation from cells: 4 months
2 - 9 days
|Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
|Therapeutic: 800 - 1600
|Toxic: Not well established
Do not use gel separator tubes. Collect specimen prior to next dose (trough) - at steady state concentration. This test is New York DOH approved.
Trazodone is a selective serotonin reuptake inhibitor antidepressant drug indicated for the treatment of major depressive disorder. The pharmacokinetics of trazodone is influenced by drug-drug interactions that induce or inhibit CYP3A4 metabolism. Adverse effects may include sedation, fatigue, headache, blurred vision, nausea and cardiac arrhythmia. The risk of serotonin syndrome is increased with concomitant use of other serotonergic drugs. Concomitant use of trazodone with anticoagulants and nonsteroidal anti-inflammatory drugs may increase the risk of bleeding.