Tularemia Antibodies, IgG and IgM
Test Mnemonic
TULGMA
CPT Codes
- 86668 - QTY (2)
Aliases
- TULGMA
- Franciscella tularensis Antibodies
Includes
- F. tularensis, IgG
- F. tularensis, IgM
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.6 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 month |
Days Performed
Mon, Wed, Fri
Turnaround Time
2 - 7 days
Methodology
| Name | Description |
|---|---|
| Semi Quantitative Enzyme Linked Immunosorbent Assay |
Reference Range
| F. tularensis IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < or = 9 U/mL; Negative - No significant level of IgG antibody to F. tularensis detected | 10 - 15 U/mL; Equivocal - Questionable presence of IgG antibody to F. tularensis. Repeat testing in 10-14 days may be helpful | > or = 16 U/mL; Positive - Presence of IgG antibody to F. tularensis detected, suggestive of current or past exposure/immunization | |||
| F. tularensis IgM | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < or = 9 U/mL; Negative - No significant level of IgM antibody to F. tularensis detected | 10 - 15 U/mL; Equivocal - Questionable presence of IgM antibody to F. tularensis. Repeat testing in 10-14 days may be helpful | > or = 16 U/mL; Positive - Presence of IgM antibody to F. tularensis detected, suggestive of current or recent exposure/immunization |
Special Info
If the initial testing is equivocal or positive for IgG and/or IgM, then Francisella tularensis Antibodies by Agglutination will be performed at an additional cost. Contaminated, heat-inactivated, or turbid specimens will be rejected. This test is New York DOH approved.
Clinical Info
Cross reactivity with Brucella and Yersinia antibodies may occur. Therefore, results should be interpreted with caution and correlated with clinical information. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are performed in the same laboratory at the same time.