Varicella Zoster IgM Ab, CSF
Test Mnemonic
CVZVM
CPT Codes
- 86787 - QTY (1)
LOINC ®
31695-0
Aliases
- Chicken Pox, Shingles
- VZV Antibody IgM, CSF
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Cerebrospinal fluid (CSF) | Clean container | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
Days Performed
Mon - Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Semi Quantitative Enzyme Linked Immunosorbent Assay |
Reference Range
| Varicella Zoster IgM Ab, CSF | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Negative: 0.90 or less | ISR |
Special Info
Specimen types other than CSF are unacceptable. Contaminated, heat-inactivated or hemolyzed specimens will be rejected.
Clinical Info
The detection of antibodies to VZV in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier. Interpretation: Negative: <=0.90 ISR; 0.91-1.09 ISR: Equivocal; 1.10 or greater ISR: Positive - Significant level of IgM antibody to VZV detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.