Special Communication
Inhibin B – Changes to Reference Ranges
Effective February 16, 2021, methodology and reference intervals for Inhibin B (INHIBB) will change.
Test results obtained with the new ANSH Ultra-Sensitive Inhibin B ELISA method and the previous Beckman Coulter Inhibin G Gen II ELISA method cannot be used interchangeably.
Beginning February 16 through May 16, 2021, specimens will be analyzed with both methods to establish a new baseline for individual patient results. Results from the previous method and reference intervals will be posted in a comment on the patient’s chart.
This change increases the detection of inhibin B in all clinically relevant cases and expands the testing range to improve sensitivity.
Additional details are available in the February 2021 Technical Update.
Changes to Reference Ranges
Effective February 16, 2021.
Inhibin B (INHIBB)
Female
1 day – 12 years:
1 – 182 pg/mL
13 – 41 years (regular cycle, follicular phase):
8 – 223 pg/mL
42 – 51 years (regular cycle, follicular phase):
1 – 107 pg/mL
51 – 76 years (postmenopausal):
1 – 11 pg/mL
Male
< 15 days:
68 – 373 pg/mL
15 days – 6 months:
42 – 516 pg/mL
7 months – 7 years:
24 – 300 pg/mL
8 – 30 years:
47 – 383 pg/mL
31 – 72 years:
10 – 357 pg/mL
Methodology
ANSH ultrasensitive Inhibin B ELISA method
formerly Beckman Coulter Inhibin B Gen II ELISA method