Special Communication
January 2022: Changes to Specimen Requirements, Reference Ranges, and More
All changes effective February 22, 2022.
Changes to Specimen Requirements
Amylase Isoenzymes (AMYISO)
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
0.5 mL
Collection Container:
Light Green Lithium Heparin PST
Note: Plasma specimens in Sodium Heparin tubes are no longer acceptable.
Transport Temperature:
Refrigerated
Additional Information:
Remove plasma ASAP or within 2 hours of collection.
Beta hCG Quant Tumor Marker (BHCG)
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
0.4 mL
Collection Container:
Light Green Lithium Heparin PST
Note: Plasma specimens in Sodium Heparin tubes are no longer acceptable.
Transport Temperature:
Refrigerated
Additional Information:
Separate plasma from cells within 2 hours of collection and transfer to a standard aliquot tube.
C Telopeptide, Beta Cross Linked (CTELO)
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
0.5 mL
Collection Container:
Lavender K2EDTA
Transport Temperature:
Refrigerated
Additional Information:
Morning fasting specimen preferred.
Patient Prep:
For patients receiving therapy with high biotin doses (e.g. greater than 5 mg/day), the specimen should not be drawn until at least 8 hours after the last biotin administration.
Centrifuge and separate plasma from cells ASAP or within 2 hours of collection. Transfer plasma to a standard aliquot tube.
HIV 1 Drug Resistance by Next Generation Sequencing (HIVNGS)
Specimen Requirements
Specimen Type:
Plasma
Volume:
3 mL
Minimum Volume:
2.5 mL
Collection Container:
Lavender K2EDTA
Transport Temperature:
Frozen
Additional Information:
Separate plasma from cells within 24 hours and transfer plasma to a standard aliquot tube. Please submit the most recent viral load and test date, if available.
T3, Uptake (T3U)
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
0.5 mL
Collection Container:
Light Green Lithium Heparin PST
Note: Plasma specimens in Sodium Heparin tubes are no longer acceptable.
Transport Temperature:
Refrigerated
Additional Information:
Separate plasma from cells ASAP or within 2 hours of collection and transfer to a standard aliquot tube.
Changes to Reference Ranges
Amylase Isoenzymes (AMYISO)
Total Amylase
13-99 Years:
28 – 100 U/L
Pancreatic Amylase
18-99 Years:
13 – 53 U/L
Bioavailable Testosterone/SHBG, Female & Child (BTSTFC)
Sex Hormone Binding Globulin – Female
18-49 Years:
25 – 122 nmol/L
50-99 Years:
17 – 125 nmol/L
Sex Hormone Binding Globulin – Male
18-49 Years:
17 – 56 nmol/L
50-99 Years:
19 – 76 nmol/L
CK Isoenzymes (CKISO)
Creatine Kinase – Female
18 Years and Older:
26 – 192 U/L
Creatine Kinase – Male
18 Years and Older:
39 – 308 U/L
C Telopeptide, Beta Cross Linked (CTELO)
Female, Premenopausal:
25 – 573 pg/mL
Schistosoma IgG Ab (SCHIST)
Less than 9 U:
Negative – No significant level of Schistosoma IgG antibody detected.
9 – 11 U:
Equivocal – Recommend repeat testing in 2-4 weeks with a fresh sample.
Greater than 11 U:
Positive – IgG antibodies to Schistosoma detected, which may suggest current or past infection.
Changes to Test Build
CYP2C19 – Cytochrome P450 2C19 (2C19CY)
Components Affected
Add component CYP2C19 Phenotype
Test Discontinuations
von Willebrand Disease, Type 2A (VWF) Sequencing Exon 28 with Reflex to 9 Exons (VWFE28)
Reason for Discontinuation:
No longer offered by vendor
Alternative Test:
von Willebrand Disease (VWF) Sequencing (VWFSEQ) – Available 02/26/22
NAbFeron Ab (NABFAB)
Reason for Discontinuation:
No longer offered by vendor