Acute Leukemia NGS Panel, Bone Marrow
- 81455 - QTY (1)
Cleveland Clinic Laboratories
|Volume||Type||Container||Collect Temperature||Transport Temperature||Special Instructions|
|4 mL||Aspirate, bone marrow||EDTA (Lavender)||Ambient||Refrigerated||Refrigerate ASAP|
|Refrigerated||Stored up to 3 days. If testing is delayed, awaiting specimen triaging, store as NUCBUF|
|Ambient||If specimen is to be stored longer than 24 hours, it should be placed at 2-8 C for up to 3 days. If testing is delayed, awaiting specimen triaging, store as NUCBUF|
Mon - Fri
|Next Gen Sequencing|
RNA_genes: ABL1, ABL2, AFDN (MLLT4), ALK, BCL11B, BCL2, BCL3, BCL6, BCR, BIRC3, BLNK, CBFB, CBL, CCND1, CCND2, CCND3, CD274, CD28, CDK6, CDKN2A, CEBPA, CEBPD, CEBPE, CEBPG, CHD1, CHIC2, CIITA, CREBBP, CRLF2, CSF1R, CTLA4, DEK, DGKH, DUSP22, EBF1, EIF4A1, EPOR, ERG, ETV6, FGFR1, FLT3, FOXP1, GLIS2, HLF, ID4, IKZF1, IKZF2, IKZF3, IL2RB, IRF4, IRF8, ITK, JAK2, KAT6A, KLF2, KMT2A, LMO1, LMO2, LYN, MALT1, MECOM, MEF2D, MLF1, MLLT10, MRTFA (MKL1), MUC1, MYC, MYH11, NF1, NFKB2, NOTCH1, NTRK3, NUP214, NUP98, NUTM1, P2RY8, PAG1, PAX5, PBX1, PDCD1, PDCD1LG2, PDGFRA, PDGFRB, PICALM, PML, PRDM16, PTK2B, RARA, RBM15, ROS1, RUNX1, RUNX1T1, SEMA6A, SETD2, STIL, SYK, TAL1, TCF3, TFG, TLX1, TLX3, TP63, TSLP, TYK2, VAV1, ZCCHC7, ZNF384. DNA_genes: ABL1, ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CDKN2A, CEBPA, CSF3R, CUX1, DDX41, DNMT3A, EED, ETNK1, ETV6, EZH2, FBXW7, FLT3, GATA1, GATA2, GNAS, IDH1, IDH2, IKZF1, JAK2, JAK3, KDM6A, KIT, KMT2A, KRAS, LUC7L2, MPL, MYD88, NF1, NOTCH1, NPM1, NRAS, PAX5, PHF6, PIGA, PPM1D, PRPF8, PTEN, PTPN11, RAD21, RIT1, RUNX1, SETBP1, SF3B1, SH2B3, SMC1A, SMC3, SRSF2, STAG2, STAT3, STAT5B, SUZ12, TET2, TP53, U2AF1, WT1, ZRSR2
DNA and RNA combination testing to evaluate for single nucleotide variants, small insertions and deletions, and common fusions in acute hematologic malignancies (acute myeloid and acute lymphoblastic leukemias); content includes all of the fusion targets of Hematologic Neoplasm Fusion NGS Panel as well as all of the DNA targets in the Chronic Myeloid NGS Panel.
Not to be ordered concurrently with the Hematologic Neoplasm Fusion NGS Panel or the Chronic Myeloid NGS Panel, since this panel includes all targeted regions from those panels.