Asparaginase Enzyme Activity




Test Mnemonic

ASNASE

CPT Codes

  • 82657 - QTY (1)

Aliases

  • Erwinaze
  • Oncaspar
  • Pegaspargase

Includes

  • Asparaginase Activity

Performing Laboratory

NEXT Molecular Analytics


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) RefrigeratedRecord time and date of most recent asparaginase administration. Immediately after collection, invert tube gently five times then allow specimen to clot for 30 to 60 minutes. Centrifuge, then use a disposable pipette to transfer 1 mL serum to standard aliquot tube.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumNo additive (Red) RefrigeratedRecord time and date of most recent asparaginase administration. Allow specimen to clot for 30 to 60 minutes. Centrifuge, then use a disposable pipette to transfer 1 mL serum to standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.3 mL     

Stability

Environmental Condition Description
Refrigerated14 days
Frozen3 years
Ambient7 days

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Coupled enzymatic assay 

Special Info

Shipping kits with sample submission forms are stored in Main Campus Send Outs laboratory. Record the sample date and time of collection on the sample submission form as well as the time and date of the most recent asparaginase administration.

Clinical Info

Lower limit of quantitation is 0.013 IU/mL. This test is useful in determining asparaginase activity present during treatment and identifying patients with hypersensitivity to asparaginase.