Complement C7 Functional
Test Mnemonic
C7FUN
CPT Codes
- 86161 - QTY (1)
LOINC ®
26996-9
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Place specimen on ice after draw. | Frozen | Patient should be fasting. Do not use serum separator tubes. Separate serum from cells and freeze immediately. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | 14 days |
| Ambient | Unacceptable |
| Refrigerated | Unacceptable |
Days Performed
Mon - Sat
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Turbidimetry (TURB) |
Reference Range
| Complement C7 Functional | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 36 - 60 | U/mL |
Special Info
Patient should be fasting. Place specimen on ice after draw. Do not use serum separator tubes. Remove serum from cells ASAP and freeze.
Clinical Info
Low levels of complement may be due to inherited deficiencies, acquired deficiencies, or due to complement consumption (eg, as a consequence of infectious or autoimmune processes). Absent C7 levels in the presence of normal C3 and C4 values are consistent with a C7 deficiency. Absent C7 levels in the presence of low C3 and C4 values suggest complement consumption. Absent (or low) C7 functional levels in the presence of normal C7 antigen levels should be replicated with a new serum specimen to confirm that C7 inactivation did not occur during shipping.