Direct Immunofluorescence of Biopsy
CPT Codes
- 88346 - QTY (1)
Aliases
- Cutaneous DIF
- Lupus Band Test
- Skin DIF
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 - 4 mm | Biopsy | Saline-moistened gauze in clean container | Refrigerated | Deliver specimen to laboratory within 24 hours of collection. Refrigerate fresh specimens until transport. Indicate 'DIF' in special request area. Indicate patients name and unique identifier (MRN) on specimen container. |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Direct Immunofluorescence |
Reference Range
Special Info
Submit Surgical Pathology Requisition or accompany with an electronically generated test request. Specimen will be stained for IgG, IgA, IgM, CD3 and Fibrinogen; or, for kidney, albumin. Requisition must be completely filled out with date of procedure, patient's name, clinic number, date of birth or age, clinical history, clinician, procedure location, initial of nurse who assisted procedure, specimen submitted and any requests for special procedures (i.e. D.I.F.)
Clinical Info
Used to demonstrate in vivo fixation of antibody in autoimmune diseases. Interpretation by Pathologist.