Estradiol by Tandem Mass Spectrometry | Cleveland Clinic Laboratories

Estradiol by Tandem Mass Spectrometry Print

Test Mnemonic

ESTMS

CPT Codes

82670 - QTY (1)

Performing Laboratory

ARUP

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL	Serum	SST (Gold)		Refrigerated	Separate serum or plasma from cells within 2 hours after collection.

Alternate Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL	Plasma	EDTA (Lavender)		Refrigerated	Separate serum or plasma from cells within 2 hours of collection.
0.5 mL	Plasma	Sodium or Lithium heparin (Green)		Refrigerated	Separate serum or plasma from cells within 2 hours of collection.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.3 mL

Stability

Environmental Condition	Description
Ambient	After separation from cells: 48 hours
Frozen	After separation from cells: 1 month
Refrigerated	After separation from cells: 1 week

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name	Description
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference Range

Estradiol
Sex	Age From	Age To	Type	Range	Range Unit
Female			Normal	Tanner Stage I: < 56.0	pg/mL
Female			Normal	Tanner Stage II: 2.0 - 133.0	pg/mL
Female			Normal	Tanner Stage III: 12.0 - 277.0	pg/mL
Female			Normal	Tanner Stage IV and V: 2.0 - 259.0	pg/mL
Female	7 Years	9 Years	Normal	< 36.0	pg/mL
Female	10 Years	12 Years	Normal	1.0 - 87.0	pg/mL
Female	13 Years	15 Years	Normal	9.0 - 249.0	pg/mL
Female	16 Years	17 Years	Normal	2.0 - 266.0	pg/mL
Female	18 Years	99 Years	Normal	Early Follicular Phase: 30.0 - 100.0	pg/mL
Female	18 Years	99 Years	Normal	Late Follicular Phase: 100.0 - 400.0	pg/mL
Female	18 Years	99 Years	Normal	Luteal Phase: 50.0 - 150.0	pg/mL
Female	18 Years	99 Years	Normal	Postmenopausal: 2.0 - 21.0	pg/mL
Male			Normal	Tanner Stage I: < 8.0	pg/mL
Male			Normal	Tanner Stage II: < 10.0	pg/mL
Male			Normal	Tanner Stage III: 1.0 - 35.0	pg/mL
Male			Normal	Tanner Stage IV and V: 3.0 - 35.0	pg/mL
Male	7 Years	9 Years	Normal	< 7.0	pg/mL
Male	10 Years	12 Years	Normal	< 11.0	pg/mL
Male	13 Years	15 Years	Normal	1.0 - 36.0	pg/mL
Male	16 Years	17 Years	Normal	3.0 - 34.0	pg/mL
Male	18 Years	99 Years	Normal	10.0 - 42.0	pg/mL

Special Info

Separate serum or plasma from cells within 2 hours of collection. This test is New York DOH approved.