FISH for 1p/19q
Test Mnemonic
1P19Q
CPT Codes
- 88377 - QTY (1)
- 88377(PC) - QTY (1)
Includes
- FISH for 1p
- FISH for 19q
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Four | Slide (s), unstained | Clean container | Ambient | Ambient | One formalin-fixed, paraffin embedded block containing representative tissue OR unstained 4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be fixed in formalin NOT B5 or PREFER fixative |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Four | One formalin-fixed, paraffin embedded block containing representative tissue OR unstained 4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be fixed in formalin NOT B5 or PREFER fixative |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Preferred |
Days Performed
5 days per week
Turnaround Time
3 - 5 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Clinical Info
Interphase FISH analysis utilizing enumeration probes for 1p36 & 19q13 useful in the diagnosis of astrocytomas, oligodendrogliomas, ependymomas, or mixed gliomas. If no cells are available for analysis, no analysis charges will be incurred.