FISH for Chronic Lymphocytic Leukemia, Bone Marrow




Test Mnemonic

CLLFSM

CPT Codes

  • 88271 - QTY (7)
  • 88275 - QTY (3)
  • 88291 - QTY (1)
  • 88237 - QTY (1)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowSodium heparin (Green)AmbientAmbient 
2 - 3 mLBone marrowEDTA (Lavender)AmbientAmbient 

Stability

Environmental Condition Description
Ambient48 hours, preferred
Refrigerated48 hours, Not preferred but acceptable
FrozenNot acceptable

Days Performed

5 days per week

Turnaround Time

5 - 7 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Special Info

This test currently includes FISH testing for 17p(TP53), 11q(ATM), 12 centromere and 13q(D13S319,LAMP1). IgH/CCND1 is being added to this panel

Clinical Info

Prognostic indicator for patients with CLL (Chronic Lymphocytic Leukemia).