FISH for IGH/CCND1 Bone Marrow




Test Mnemonic

FSMCLM

CPT Codes

  • 88271 - QTY (2)
  • 88275 - QTY (1)
  • 88291 - QTY (1)
  • 88237 - QTY (1)

Aliases

  • FISH for t(11;14) translocation

Includes

  • LSI CCND1 (11q13)
  • LSI IGH (14q32)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowEDTA (Lavender)AmbientAmbient 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowSodium heparin (Green)AmbientAmbient 

Stability

Environmental Condition Description
Ambient48 hours
RefrigeratedAcceptable
FrozenUnacceptable

Days Performed

5 days per week

Turnaround Time

3 - 5 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

This assay uses a dual color, dual fusion probe to detect the IGH/CCND1 translocation associated with mantle cell lymphoma. This test should not be used to monitor minimal residual disease. If no cells are available for analysis, no analysis charges will be incurred.