FISH for MYC (8q24) Blood




Test Mnemonic

MYCFSH

CPT Codes

  • 88291 - QTY (1)
  • 88271 - QTY (2)
  • 88275 - QTY (1)
  • 88237 - QTY (1)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
5 - 7 mLBlood, peripheralEDTA (Lavender)AmbientAmbient 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
5 - 7 mLBlood, peripheralSodium heparin (Green)AmbientAmbient 

Stability

Environmental Condition Description
Ambient48 hours
RefrigeratedAcceptable
FrozenNot acceptable

Days Performed

5 days per week

Turnaround Time

3 - 5 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Special Info

Specimens submitted for MYC amplification should not use this test code.

Clinical Info

This assay uses a dual color, break-apart probe to detect translocations involving the MYC gene. MYC translocations are seen in a wide variety of malignant lymphomas including Burkitt lymphoma, diffuse large B-cell lymphoma, and others.