FISH for MYC (8q24) Tissue
Test Mnemonic
MYC
CPT Codes
- 88377 - QTY (1)
Aliases
- TMYCF
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| One | Paraffin block | Clean container | Containing representative tissue. | ||
| Four | Slide (s), unstained | Clean container | 4 um tissue sections on electrostatically charged slides containing representative tumor. Tissue must be formalin fixed. Samples must not be fixed in B5 or Prefer fixative. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Blocks and slides should be transported at ambient temperature. |
Days Performed
5 days per week
Turnaround Time
3 - 5 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Special Info
4 um tissue sections on electrostatically charged slides containing representative tumor. Tissue must be formalin fixed. Samples must not be fixed in B5 or Prefer fixative.
Clinical Info
This test is used for the identification of MYC translocations, as seen in Burkitt lymphoma, diffuse large B-cell lymphoma, and other hematolymphoid neoplasms. This assay employs a break-apart probe strategy and does not identify the translocation partner gene.