FISH for MYC (8q24) Tissue




Test Mnemonic

MYC

CPT Codes

  • 88377 - QTY (1)

Aliases

  • TMYCF

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
OneParaffin blockClean container  Containing representative tissue.
FourSlide (s), unstainedClean container  4 um tissue sections on electrostatically charged slides containing representative tumor. Tissue must be formalin fixed. Samples must not be fixed in B5 or Prefer fixative.

Stability

Environmental Condition Description
AmbientBlocks and slides should be transported at ambient temperature.

Days Performed

5 days per week

Turnaround Time

3 - 5 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Special Info

4 um tissue sections on electrostatically charged slides containing representative tumor. Tissue must be formalin fixed. Samples must not be fixed in B5 or Prefer fixative.

Clinical Info

This test is used for the identification of MYC translocations, as seen in Burkitt lymphoma, diffuse large B-cell lymphoma, and other hematolymphoid neoplasms. This assay employs a break-apart probe strategy and does not identify the translocation partner gene.