FISH for PDGFRB Rearrangement Blood
Test Mnemonic
PDGFRB
CPT Codes
- 88271 - QTY (2)
- 88275 - QTY (1)
- 88291 - QTY (1)
- 88237 - QTY (1)
Aliases
- FISH FOR PDGFRB
- Imatinib Mesylate Responsive Gene
- PDGFR beta
Includes
- Result
- Interpretation
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | EDTA (Lavender) | Ambient | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | Sodium heparin (Green) | Ambient | Ambient |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Acceptable |
| Refrigerated | Acceptable |
| Frozen | Unacceptable |
Days Performed
3 days per week
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Reference Range
| PDGFRB Rearrangement by FISH | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative for PDGFRB Rearrangement |
Clinical Info
A dual color, break-apart probe flanking the centromeric and telomeric sides of the PDGFRB locus is used to evaluate for a translocation involving the PDGFRB gene.