FISH for RARA Bone Marrow




Test Mnemonic

RARFSM

CPT Codes

  • 88271 - QTY (2)
  • 88275 - QTY (1)
  • 88291 - QTY (1)
  • 88237 - QTY (1)

Includes

  • FISH for RARA (17q21)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowEDTA (Lavender)AmbientAmbient 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowSodium heparin (Green)AmbientAmbient 

Stability

Environmental Condition Description
Ambient48 hours
RefrigeratedAcceptable
FrozenNot acceptable

Days Performed

5 days per week

Turnaround Time

5 - 7 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

This assay employs a dual color, break-apart FISH probe to detect translocations involving the RARA gene at chromosome 17q21, as seen in acute promyelocytic leukemia. If no cells are available for analysis, no analysis charges will be incurred.