FISH for TP63 and DUSP22-IRF4 Panel




Test Mnemonic

TPDUFP

CPT Codes

  • 88377 - QTY (2)

Includes

  • LSI 6p25.3
  • LSI 3q28

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
4 slidesParaffin block, formalin fixedSlides, unstainedAmbientAmbientPre and Post H&E with four unstained slides with defined marked areas for analysis

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
4 slides    Pre and Post H&E with four unstained slides with defined marked areas for analysis

Stability

Environmental Condition Description
AmbientFFPE slides at room temperature

Days Performed

5 days per week

Turnaround Time

3 - 5 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

Interphase FISH analysis utilizing dual color, break-apart probe sets for the DUSP22/IRF genes at 6p25.3 and the TP63 gene at 3q28. Rearrangements of these genes may be observed in ALK-negative, anaplastic large cell lymphoma. The translocation partner gene cannot be identified in this assay. If no cells are available for analysis, no analysis charges will be incurred.