Glutamic Acid Decarboxylase Antibody
Test Mnemonic
GADCAB
CPT Codes
- 86341 - QTY (1)
LOINC ®
13926-1
Aliases
- GAD 65 Antibody
- GAD Ab
- Glutamic Acid Decarboxylase Antibody
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 7 days |
| Frozen | 14 days |
Days Performed
Tue, Fri
Turnaround Time
1 - 8 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| Glutamic Acid Decarboxylase Aby, Qualitative | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Negative | ||||
| Glutamic Acid Decarboxylase Antibody | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <=5.0 | IU/mL |
Special Info
Patients taking a Biotin dose >300 mg/day should consult with their physician or the laboratory prior to having a sample taken.
Clinical Info
Anti-glutamic acid decarboxylase antibody (GAD65) test usually in conjunction with another test such as IA-2 antibody is used as an aid in establishing the autoimmune nature of previously-diagnosed type I diabetes mellitus or in predicting of progression to type I diabetes mellitus in patients with certain autoimmune diseases including autoimmune gastritis among others. It is also used as an aid in diagnosis of stiff person syndrome and certain autoimmune nervous system diseases. Clinical correlation is required.
Clinical Limitation
Lipemic or grossly hemolyzed samples will be rejected.