Histone IgG Aby




Test Mnemonic

HISTN

CPT Codes

  • 86235 - QTY (1)

LOINC ®

29996-6

Aliases

  • H2A-H2B- DNA Auto Antibodies
  • Histone DNA Complex IgG Auto Aby

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Ambient24 hours
Refrigerated7 days
Frozen1 year; 2 freeze thaw cycles are acceptable

Days Performed

Thu

Turnaround Time

1 - 8 days

Methodology

Name Description
Enzyme-Linked Immunosorbent Assay (ELISA) 

Reference Range

Histone IgG Antibody
Sex Age From Age To Type Range Range Unit
       Normal<1.0Units

Special Info

Negative:<1.0 units, Weak positive: 1.0-1.5 units, Moderate positive: 1.6-2.5 units, Strong positive: >2.5 units Results are obtained with the Inova QUANTA Lite Histone ELISA kit. Histone values obtained with different manufacturers' assay methods may not be used interchangeably. The magnitude of the reported IgG levels cannot be correlated to an endpoint titer.

Clinical Info

Anti-histone IgG antibody test is used as an aid in the diagnosis of idiopathic and drug-induced systemic lupus erythematosus. It may be positive in other systemic autoimmune diseases. Clinical correlation is required.