Lacosamide
Test Mnemonic
LACOS
CPT Codes
- 80235 - QTY (1)
Aliases
- Vimpat
Includes
- Lacosamide
- Desmethyllacosamide
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 72 hours |
| Refrigerated | 2 weeks |
| Frozen | 6 months |
Days Performed
Mon, Wed, Fri
Turnaround Time
1 - 4 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
Reference Range
| Desmethyllacosamide | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | <2.6 | ug/mL | |
| Lacosamide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 2.2-19.8 | ug/mL |
Special Info
Collect immediately prior to next dose. Do not collect in a gel separator tube. Centrifuge and transfer serum to a CCL tube and refrigerate within 2 hours of collection.
Clinical Info
Antiepileptic drug. Expected concentration of patients receiving 200-400 mg/day is 2.2-19.8 ug/mL for Lacosamide and up to 2.5 ug/mL for Desmethyl Lacosamide. Toxic range not established.