Lactate Dehydrogenase Isoenzymes




Test Mnemonic

LDISO

CPT Codes

  • 83615 - QTY (1)
  • 83625 - QTY (1)

Includes

  • Lactate Dehydrogenase
  • LD1
  • LD2
  • LD3
  • LD4
  • LD5

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) AmbientAllow specimen to clot at room temperature and then centrifuge ASAP.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumNo additive (Red) AmbientAllow specimen to clot at room temperature and then centrifuge ASAP.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.6 mL     

Stability

Environmental Condition Description
AmbientAfter separation from cells: 1 week
RefrigeratedUnacceptable
FrozenUnacceptable

Days Performed

Sun - Sat

Turnaround Time

2 - 3 days

Methodology

Name Description
Enzymatic 
Electrophoresis 

Reference Range

Lactate Dehydrogenase
Sex Age From Age To Type Range Range Unit
   Days30 DaysNormal200 - 465U/L
 1 Months17 MonthsNormal200 - 450U/L
 18 Months24 MonthsNormal165 - 430U/L
 3 Years10 YearsNormal165 - 430U/L
 11 Years16 YearsNormal127 - 287U/L
 17 Years99 YearsNormal105 - 230U/L
LD1
Sex Age From Age To Type Range Range Unit
       Normal14 - 27%
LD2
Sex Age From Age To Type Range Range Unit
       Normal29 - 42%
LD3
Sex Age From Age To Type Range Range Unit
       Normal18 - 30%
LD4
Sex Age From Age To Type Range Range Unit
       Normal8 - 15%
LD5
Sex Age From Age To Type Range Range Unit
       Normal6 - 23%

Special Info

Do not refrigerate or freeze specimen. LD-1 and LD-2 are elevated in hemolyzed specimens and serum which has not been separated from cells. LD-3, LD-4, and LD-5 are labile at low temperatures, and are erroneously low in specimens that have been refrigerated or frozen.

Clinical Info

Determine source of increased LD