LPT to Beryllium, BAL
Test Mnemonic
BALBE
CPT Codes
- 86353 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 200 mL | Bronch (BAL) | Clean container | Ambient | Collect Monday - Thursday only. Deliver the specimen to the lab within 24 hours post collection. Do not aliquot. Specimen must remain at ambient temperature. Do not refrigerate. Do not freeze. Collect sample in a sterile container using aseptic technique. Sample cannot be shared with other testing. This test cannot be added on to other testing. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 80 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
Days Performed
Mon - Thu
Turnaround Time
10 - 14 days
Methodology
| Name | Description |
|---|---|
| Radioactive thymidine uptake in cell culture |
Reference Range
| Beryllium 1.0 uM D3 | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <= 3.0 | SI | |||
| Beryllium 1.0 uM D5 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <=3.0 | SI | |||
| Beryllium 10 uM D3 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <= 3.0 | SI | |||
| Beryllium 10 uM D5 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <=3.0 | SI | |||
| Beryllium 100 uM D3 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <=3.0 | SI | |||
| Beryllium 100 uM D5 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <=3.0 | SI | |||
| PHA Simulation Index | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | >= 10.0 | SI |
Special Info
Contact testing laboratory at least one week prior to collecting specimen at (216) 444-2502. Specimen should not be collected or delivered on weekends or holidays.
Clinical Info
Lymphocyte proliferation test to Beryllium is a cellular assay used as an aid in diagnosis of prior sensitization to Beryllium in the environment. Beryllium-sensitized individuals may remain asymptomatic for extended periods and never develop chronic berylliosis. Clinical, epidemiological, and radiological correlation is required. Bronchoalveolar lavage testing may offer higher sensitivity than whole blood testing where pulmonary disease is present.