Monoclonal Protein, Urine




Test Mnemonic

URMPA

CPT Codes

  • 86335 - QTY (1)

Aliases

  • Immunoelectrophoresis, Urine
  • Immunofixation Electrophoresis (IFE), Urine
  • Myeloma Typing, Urine

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
15 mLUrine, randomClean container Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
7 mL     

Stability

Environmental Condition Description
Ambient1 day
Refrigerated14 days
Frozen30 days

Days Performed

Mon - Fri

Turnaround Time

1 - 7 days

Methodology

Name Description
Immunofixation 

Reference Range

Monoclonal Protein
Sex Age From Age To Type Range Range Unit
       FreetextFree monoclonal light chains are not identified 

Clinical Info

Evaluation of monoclonal gammopathies, light chain amyloid disease, and serum hypogammaglobulinemia. Individuals with normal kidney function may have no protein or a trace of albumin in their urine. Kappa degradation fragments are benign fragments of light chains that may be seen in some normal urine samples. Monoclonal free immunoglobulin light chains may be seen in the urine even when not present in the serum, and may co-exist with an intact monoclonal immunoglobulin.