Myeloperoxidase (MPO), for cardiac risk evaluation




Test Mnemonic

MPO

CPT Codes

  • 83876 - QTY (1)

Includes

  • Myeloperoxidase (MPO)

Performing Laboratory

LabCorp


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLPlasmaEDTA (Lavender)Place specimen on ice after draw.RefrigeratedCRITICAL REFRIGERATED. Place specimen on ice to chill. Within two hours of collection, centrifuge and aliquot approximately 2/3 of the upper plasma layer into a standard aliquot tube and refrigerate. Separate specimens must be submitted when multiple tests are ordered.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLPlasmaSodium or Lithium heparin (Green)Place specimen on ice after draw. CRITICAL REFRIGERATED. Do not use gel barrier tube. Place specimen on ice to chill. Within two hours of collection, centrifuge and aliquot approximately 2/3 of the upper plasma layer into a standard aliquot tube and refrigerate. Separate specimens must be submitted when multiple tests are ordered.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.2 mL     

Stability

Environmental Condition Description
AmbientUnacceptable
Frozen6 months
Refrigerated5 days

Days Performed

Varies

Turnaround Time

3 - 5 days

Methodology

Name Description
Latex Enhanced Immunoturbidimetric Method 

Reference Range

Myeloperoxidase
Sex Age From Age To Type Range Range Unit
       NormalLow risk: < 470pmol/L
       NormalModerate risk: 470 - 539pmol/L
       NormalHigh risk: >= 540pmol/L

Special Info

CRITICAL REFRIGERATED. Do not use gel separator tubes.

Clinical Info

Elevated levels of plasma MPO are a sensitive indicator of inflammatory disorders.

Clinical Limitation

Erratic results can be observed if plasma is not centrifuged and separated from red cells immediately.