Neutrophil Cytoplasmic Antibody




Test Mnemonic

ANCA

CPT Codes

  • 86036 - QTY (2)

Aliases

  • ANCA
  • Anti-Neutrophil Cytoplasmic Ab

Includes

  • C-ANCA and P-ANCA by Indirect Immunofluorescence Assay
  • If either is positive, Proteinase-3 Ab and Myeloperoxidase Ab by multiplex

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumSST (Gold) Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient24 hours
Refrigerated7 days
Frozen30 days

Days Performed

Mon - Fri

Turnaround Time

1 - 4 days

Methodology

Name Description
Indirect Immunofluorescence Assay (IFA)  

Reference Range

Myeloperoxidase Ab
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormal< 1.0AI
Proteinase-3 Ab
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormal< 1.0AI

Special Info

If either C-ANCA or P-ANCA are positive or questionable by IFA, then Proteinase-3 Ab and Myeloperoxidase Ab by multiplex will be performed and billed.

Clinical Info

Diagnosis and monitoring of patients with Wegener's Granulomatosis, systemic arthritis and glomerulonephritis. Also present in Polyarthritis Nodosa and other vasculitides. Atypical indirect immunofluorescence may be seen with inflammatory bowel disease and a common mediated liver disease, usually in the P-ANCA pattern