Platelet Aggregation
Test Mnemonic
AGGPLP
CPT Codes
- 82397 - QTY (6)
- 85576 - QTY (10)
- 85390 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 18 mL | Whole blood | Sodium citrate (Lt. Blue) | Ambient | Do not centrifuge. Specimen must be delivered to testing lab within 3 hours after collection and before 2:00 p.m. Sample must not be drawn after noon. | |
| 4 mL | Whole blood | EDTA (Lavender) | Ambient | THIS ASSAY REQUIRES MULTIPLE SPECIMEN TYPES. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Specimen should reach the lab within 3 hours of draw time |
| Frozen | unacceptable |
| Refrigerated | unacceptable |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Luminescence | |
| Optical Turbidimetric Aggregation |
Reference Range
| ADP 20 Max Aggreg | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 71-94 | % Max | |||
| ADP Aggregation | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 65-93 | % Max | |
| Arach Max Aggreg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 75 - 100 | % Max | |
| ATP Rel by ADP | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.1-1.3 | nM | |||
| ATP Rel by ADP 20 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.1-1.4 | nM | |||
| ATP Rel by Aracha | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.4-2.0 | nM | |||
| ATP Rel by Collagen | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.4 - 1.7 | nM | |||
| ATP Rel by Epineph | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.2-1.6 | nM | |||
| ATP Rel by Epineph 100 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0.2 - 1.7 | nM | |||
| Collagen Max Aggreg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 74-99 | % Max | |||
| Epin 100 Max Aggreg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 70-99 | % Max | |||
| EPIN Max Aggreg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 70-97 | % Max | |||
| Risto 1200 Max Agg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 76-100 | % Max | |||
| Risto 1500 Max Agg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 76 - 100 | % Max | |||
| Risto 500 Max Agg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 0-9 | % Max | |||
| Risto 900 Max Agg | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 50-100 | % Max |
Special Info
3.2% sodium citrate is the preferred anticoagulant recommended by CLSI. Test will not be performed if platelet count is less than 100,000/uL. Patient preparation: discontinue aspirin, phenylbutazone, phenothiazines, thienopyridines and glycoprotein IIb/IIIa inhibitors (if ordered to study intrinsic platelet dysfunction) and antihistamines for seven days prior to test. Sample must be accompanied by the completed Clinical History Form for Hemostasis and Thrombosis Evaluation.
Clinical Info
Evaluation of platelet function including Glanzmann's thrombasthenia, Bernard Soulier Syndrome, storage pool disorders and some types of von Willebrand's disease. This assay is not recommended for monitoring the inhibitory effect of aspirin or clopidogrel. For this purpose, please order the Aspirin/Clopidogrel Resistance panel.