Platelet Neutralization




Test Mnemonic

PLTNEU

CPT Codes

  • 85597 - QTY (1)

LOINC ®

40647-0

Aliases

  • PNP

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLPlasmaSodium citrate (Lt. Blue) Centrifuge, aliquot and freeze ASAP.Discontinue heparin or direct thrombin inhibitor therapy 48 hours prior to collection.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Clotting Assay 

Reference Range

Platelet Neutralization Delta
Sex Age From Age To Type Range Range Unit
       Normal<1.9sec
PTT LA Mix
Sex Age From Age To Type Range Range Unit
       Normal31.5-38.3sec
PTT LA Screen
Sex Age From Age To Type Range Range Unit
       Normal30.2-43.0sec

Special Info

3.2% sodium citrate is the preferred anticoagulant recommended by NCCLS. Indicate if patient is receiving heparin or coumadin or direct thrombin inhibitors.

Clinical Info

Discontinue heparin or direct thrombin inhibitor therapy 48 hours prior to collection. Test will not be performed if PTT is normal. The Platelet neutralization test is a confirmatory assay to detect the presence of a lupus anticoagulant. However, this test should not be used alone in the evaluation of lupus anticoagulant. Order circulating anticoagulant, dRVVT and hexagonal phase phospholipid neutralization tests for a more complete evaluation of lupus anticoagulant. These tests are available in the lupus anticoagulant panel, which includes an interpretation.

Clinical Limitation

n/a

Clinical Reference

n/a