Polymyositis and Dermatomyositis Panel




Test Mnemonic

MYOSPL

CPT Codes

  • 86039 - QTY (1)
  • 83516 - QTY (7)
  • 86235 - QTY (1)
  • 84182 - QTY (7)

Aliases

  • ANA
  • EJ
  • Ha
  • Jo-1
  • Ks
  • MDA5
  • Mi-2
  • NXP2
  • OJ
  • P155/140
  • PL-7
  • PL12
  • SAE1
  • SRP
  • TIF1-gamma
  • Zo

Includes

  • Myositis Interpretive Information
  • Antinuclear Antibody (ANA), HEp-2, IgG
  • ANA Interpretive Comment
  • Ha (tyrosyl-tRNA synthetase) Ab
  • Ks (asparaginyl-tRNA synthetase) Ab
  • Zo (phenylalanyl-tRNA synthetase) Ab
  • Jo-1 Antibody, IgG
  • PL-7 (threonyl-tRNA synthetase) Antibody
  • PL-12 (alanyl-tRNA synthetase) Antibody
  • EJ (glycyl-tRNA synthetase) Antibody
  • SRP (Signal Recognition Particle) Ab
  • OJ (isoleucyl-tRNA synthetase) Antibody
  • Mi-2 (nuclear helicase protein) Antibody
  • P155/140 Antibody
  • SAE1 (SUMO activating enzyme) Antibody
  • MDA5 (CADM-140) Antibody
  • NXP-2 (Nuclear matrix protein-2) Ab
  • TIF-1 gamma (155 kDa) Antibody

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumSST (Gold) RefrigeratedSeparate from cells ASAP or within 2 hours of collection. Split serum into two 1 mL aliquots using standard aliquot tubes.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL    Note: Total minimum is 1 mL. Requires 0.5 mL per aliquot tube.

Stability

Environmental Condition Description
Refrigerated2 weeks
Frozen1 month
Ambient48 hours

Days Performed

Sun - Sat

Turnaround Time

8 - 19 days

Methodology

Name Description
Immunoblot (IB), Qualitative 
Immunoprecipitation 
Semi-Quantitative Multiplex Bead Assay 
Semi-Quantitative Indirect Fluorescent Antibody 

Reference Range

Antinuclear Antibody (ANA) HEp-2, IgG
Sex Age From Age To Type Range Range Unit
       < 1:80  
Jo-1 Antibody, IgG
Sex Age From Age To Type Range Range Unit
       0 - 40 AU/mL 

Special Info

REFLEX CRITERIA: Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma, ANA, Ha, Ks, Zo Hemolyzed, hyperlipemic, or icteric specimens will be rejected. Heat-treated or contaminated specimens are unacceptable. This test is New York DOH approved.