Protein Electrophoresis, Urine Random
Test Mnemonic
UEPG
CPT Codes
- 84156 - QTY (1)
- 84166 - QTY (1)
Aliases
- Bence Jones Protein Screen
Includes
- Urine Total protein
- % Albumin
- % Alpha 1 globulin
- % Alpha 2 globulin
- % Beta globulin
- % Gamma globulin
- Interpretation
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 15 mL | Urine, random | Clean container | Ambient | First morning void preferred. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 15 mL | Urine, 24-hour (well-mixed) | Clean container | Refrigerate during collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 7 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 days |
| Refrigerated | 14 days |
| Frozen | 30 days |
Days Performed
Mon - Fri
Turnaround Time
1 - 7 days
Methodology
| Name | Description |
|---|---|
| Electrophoresis |
Reference Range
| Protein Electrophoresis, Urine Random | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| No evidence of M-Spike |
Special Info
Urine collected in acid container not acceptable.
Clinical Info
This test is used to screen for free monoclonal immunoglobulin light chains (Bence Jones proteins) and to evaluate renal disorders. However, immunofixation electrophoresis (IFE) is a more sensitive test for the detection of small M-proteins. A trace of albumin is usually seen in normal patients. Monoclonal free immunoglobulin light chains (Bence Jones proteins) and/or intact immunoglobulins may be seen in multiple myeloma and, much less commonly, in other B-cell lymphoproliferative disorders.