Synthetic Glucocorticoid Screen, Serum




Test Mnemonic

SGLUCO

CPT Codes

  • 82542 - QTY (1)

Includes

  • Betamethasone
  • Budesonide
  • Dexamethasone
  • Fludrocortisone
  • Flunisolide
  • Fluorometholone
  • Megestrol acetate
  • Methylprednisolone
  • Prednisolone
  • Prednisone
  • Triamcinolone
  • Triamcinolone acetonide

Performing Laboratory

Mayo Clinic Dpt of Lab Med & Pathology


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumNo additive (Red) Frozen 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1.1 mL     

Stability

Environmental Condition Description
Ambient24 hours
Refrigerated7 days
Frozen14 days

Days Performed

Tue, Fri

Turnaround Time

3 - 6 days

Methodology

Name Description
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) 
Stable Isotope Dilution 

Reference Range

Betamethasone
Sex Age From Age To Type Range Range Unit
       Negative 
Budesonide
Sex Age From Age To Type Range Range Unit
       Negative 
Dexmethasone
Sex Age From Age To Type Range Range Unit
       Negative 
Fludrocortisone
Sex Age From Age To Type Range Range Unit
       Negative 
Flunisolide
Sex Age From Age To Type Range Range Unit
       Negative 
Fluorometholone
Sex Age From Age To Type Range Range Unit
       Negative 
Megestrol Acetate
Sex Age From Age To Type Range Range Unit
       Negative 
Methylprednisolone
Sex Age From Age To Type Range Range Unit
       Negative 
Prednisolone
Sex Age From Age To Type Range Range Unit
       Negative 
Prednisone
Sex Age From Age To Type Range Range Unit
       Negative 
Triamcinolone
Sex Age From Age To Type Range Range Unit
       Negative 
Triamcinolone Acetonide
Sex Age From Age To Type Range Range Unit
       Negative 

Special Info

n/a

Clinical Info

Cuttoff Concentrations: Betamethasone: 0.10 mcg/dL; Budesonide: 0.10 mcg/dL; Dexamethasone: 0.10 mcg/dL; Fludrocortisone: 0.10 mcg/dL; Flunisolide: 0.10 mcg/dL; Fluorometholone: 0.10 mcg/dL; Megestrol acetate: 0.10 mcg/dL; Methylprednisolone: 0.10 mcg/dL; Prednisolone: 0.10 mcg/dL; Prednisone: 0.10 mcg/dL; Triamcinolone: 0.30 mcg/dL; Triamcinolone acetonide: 0.10 mcg/dL. Lack of detection does not preclude use of synthetic glucocorticoid because adrenal suppression may persist for some time after the exogenous steroid is discontinued. This method cannot detect all the available synthetic steroids either available as pharmaceutical compounds or chemicals present in food. The assay confirms only the listed synthetic glucocorticoids.

Clinical Limitation

n/a

Clinical Reference

n/a