Targeted Oncology Panel Next Generation Sequencing Other
- 81455 - QTY (1)
Cleveland Clinic Laboratories
|Volume||Type||Container||Collect Temperature||Transport Temperature||Special Instructions|
|10 mm square||Block, Formalin fixed paraffin||Formalin or Paraffin Block||Ambient||Ambient||Formalin-fixed paraffin-embedded tissue slides. Transport and store slides at ambient temperature. 15 unstained sections FFPE tissue on charged, unbaked slides plus one H&E stained section with best tumor area circled by a pathologist. Provide the percentage of tumor cells present.|
|Ambient||FFPET slides are stable at ambient temperature indefinitely.|
|Refrigerated||FFPET slides are stable at 2 - 8C indefinitely.|
3 days per week
The following genes are interrogated: ABL1, AKT, AKT1, AKT3, AR, AXL, BRAF, C11orf95, CCND1, CDK4, CDK6, CTNNB1, DDR2, EGFR, ERBB2, ERBB3, ERBB4, ERG, ESR1, ETV1, ETV4, ETV5, FGFR1, FGFR2, FGFR3, FGFR4, GNA11, GNAQ, GNAS, H3-3A, H3-3B, HRAS, IDH1, IDH2, JAK1, JAK2, JAK3, KIT, KRAS, MAP2K1, MAP2K2, MET, MTOR, MYC, MYCN, NRAS, NTRK1, NTRK2, NTRK3, PDGRFA, PIK3CA, PPARG, RAF1, RELA, RET, ROS1, SMO, TERT AND TP53.
This pan-cancer assay evaluates tumor hotspots, SNVs, indels, CNVs, and gene fusions from DNA and RNA. This information can be used for diagnostic, prognostic and therapeutic purposes across a variety of solid and liquid tumors.