Tricyclic Antidepressant ID
Test Mnemonic
TAID
CPT Codes
- 80337 - QTY (1)
LOINC ®
4073-3
Aliases
- Tricyclic Antidepressants, Quantitative
Includes
- Amitriptyline
- Nortriptyline
- Imipramine
- Desipramine
- Doxepin
- Nordoxepin
- Clomipramine
- Norclomipramine
- Protriptyline
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes. Separate serum from cells within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | EDTA (Lavender) | Refrigerated | Separate plasma from cells within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 5 days |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 6 months |
Days Performed
Mon, Wed, Fri
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) |
Reference Range
| Amitriptyline | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | |
| Amitryptyline/Nortriptyline | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 95 - 250 | ng/mL | Years | 99 Years | Urgent | > 500 | ng/mL |
| Clomipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | Years | 99 Years | Urgent | Not Established | ng/mL |
| Clomipramine/Norclomipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 220 - 500 | ng/mL | Years | 99 Years | Urgent | > 900 | ng/mL |
| Desipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 100 - 300 | ng/mL | Years | 99 Years | Urgent | > 500 | ng/mL |
| Doxepin | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | Years | 99 Years | Urgent | Not Established | ng/mL |
| Doxepin/Nordoxepin | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 100 - 300 | ng/mL | Years | 99 Years | Urgent | > 500 | ng/mL |
| Imipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | |
| Imipramine/Desipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 150 - 300 | ng/mL | Years | 99 Years | Urgent | > 500 | ng/mL |
| Norclomipramine | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | Years | 99 Years | Urgent | Not Established | ng/mL |
| Nordoxepin | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Not Established | ng/mL | Years | 99 Years | Urgent | Not Established | ng/mL |
| Nortriptyline alone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | Therapeutic Range: 50 - 150 | ng/mL | |
| Protriptyline | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 70 - 240 | ng/mL | Years | 99 Years | Urgent | > 400 | ng/mL |
Special Info
Collect specimen prior to next dose - at steady state concentration. This test is New York DOH approved.