Pathology Insights Video Series

Tumors of the Lung

Presented by Sanjay Mukhopadhyay, MD

In this video, an expert pulmonary pathologist and director of Cleveland Clinic’s Pulmonary Pathology service briefly covers all lung tumor types – including all the subtypes of lung cancer – listed in the new (2021) World Health Organization classification. Dr. Mukhopadhyay then describes the primary pathologic features of these tumors with high-quality pathology images provided in most cases.

This video should be helpful for patients, surgeons, pulmonologists, oncologists, pathologists, residents, and medical students.

Pathology Insights Video Series

Update on Small Round Cell Tumors with Scott Kilpatrick, MD

Presented by Scott Kilpatrick, MD

In this video, Scott Kilpatrick, MD, Director of Orthopedic Pathology at Cleveland Clinic, provides historical context and WHO updates on the evolving classification of undifferentiated round cell sarcomas, including Ewing sarcoma and the so-called Ewing family of sarcomas.

Pathology Insights Video Series

NUT Carcinoma

Presented by Sanjay Mukhopadhyay, MD

In this video, Sanjay Mukhopadhyay, MD, Director of Pulmonary Pathology at Cleveland Clinic, highlights a rare, aggressive, malignant tumor and draws attention to a distinctive immunohistochemical profile that can serve as a tip-off to the correct diagnosis.

Pathology Insights Video Series

Two Diagnoses in One Bone Marrow

Presented by Megan Nakashima, MD

Analysis of a bone marrow requires both careful morphologic examination as well as appropriate ancillary studies.

Dr. Megan Nakashima, Staff Hematopathologist at Cleveland Clinic, discusses a complicated bone marrow case involving a patient with thrombocytopenia, monocytosis, and diarrhea. After requiring the incorporation of molecular and immunophenotypic information, two diagnoses are reached.

In addition to this case, Dr. Nakashima reviews relevant changes in the WHO 2016 classification of myeloid and associated neoplasms.

Pathology Insights Video Series

Diagnosis of Metastatic Renal Cancer

Presented by Sean Williamson, MD

Pathologic diagnosis can be challenging in the setting of poorly-differentiated and metastatic renal cancer.

Dr. Sean Williamson, Director of Genitourinary Pathology at Cleveland Clinic, discusses immunohistochemical and molecular testing used to help confirm the diagnosis.

Pathology Insights Video Series

Pathology of Vaping-Associated Lung Injury

Presented by Sanjay Mukhopadhyay, MD

Sanjay Mukhopadhyay, MD, discusses the findings of a study on the lung pathology of vaping.

Featured in an article co-authored by Dr. Mukhopadhyay and published in the American Journal of Clinical Pathology, the study focuses on the results of microscopic examination of biopsied lung tissue from individuals who developed severe lung illness associated with vaping.

This is one of the first case series in the world to examine lung biopsies from patients with vaping-associated lung illness and is the first-ever study on vaping published in a pathology journal. These findings have important public health implications and are detailed in the video.

Pathology Insights Video Series

Lung Granulomas Caused by Fungal Infection

Presented by Sanjay Mukhopadhyay, MD

Not all lung nodules are malignant.

In this video, Dr. Mukhopadhyay compares and contrasts two cases of lung granulomas caused by fungal infection. These types of fungal infection cause granulomas in the lung, which can be mistaken for each other.

Pathology Insights Video Series

Lung Cancer or Metastasis to Lung?

Presented by Sanjay Mukhopadhyay, MD

Can metastases to the lung occur from cancers that were treated several years ago?  Dr. Mukhopadhyay discusses.

Pathology Insights Video Series

Basics of Thymic Pathology

Presented by Sanjay Mukhopadhyay, MD

What are the differences between normal thymic tissue and thymoma?

Learn the basics in this brief introduction to pathology of the thymus by thoracic pathologist, Sanjay Mukhopadhyay, MD.

Pathology Insights Video Series

Challenging Cutaneous Spindle Cell Tumors

Presented by Steven Billings, MD

In this episode of Pathology Insights, Steven Billings, MD, staff pathologist for the Dermatopathology and Soft Tissue & Bone services, covers a set of challenging cutaneous spindle cell tumors, emphasizing a practical approach and key histologic features that allow accurate diagnosis.