Special Communication
August 2021: Changes to Specimen Requirements, Reference Ranges, and Test Builds
All changes effective August 16, 2021.
Changes to Specimen Requirements
Allergen, Food, Alpha-Gal IgE (GALIGE)
Specimen Requirements
Specimen Type:
Serum
Volume:
0.25 mL
Minimum Volume:
0.25 mL
Collection Container:
Gold Serum Separation Tube (SST)
Transport Temperature:
Refrigerated
Additional Information:
Separate serum from cells ASAP or within 2 hours of collection.
Macroprolactin (MACPRO)
Specimen Requirements
Specimen Type:
Serum
Volume:
1 mL
Minimum Volume:
0.5 mL
Collection Container:
Gold Serum Separation Tube (SST)
Transport Temperature:
Frozen
Additional Information:
Allow specimen to clot completely at room temperature. Separate serum from cells and transfer into a standard aliquot tube.
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
0.5 mL
Collection Container:
Lavender K2EDTA Tube or Light Green Lithium Heparin Plasma Separator Tube (PST)
Transport Temperature:
Frozen
Additional Information:
Separate plasma from cells and transfer into a standard aliquot tube.
Prolactin, Dilution Study (PROLM)
Specimen Requirements
Specimen Type:
Serum
Volume:
1 mL
Minimum Volume:
1 mL
Collection Container:
Gold Serum Separation Tube (SST)
Transport Temperature:
Frozen
Additional Information:
Allow specimen to clot completely at room temperature. Separate serum from cells and transfer into a standard aliquot tube.
Alternative Specimen Requirements
Specimen Type:
Plasma
Volume:
1 mL
Minimum Volume:
1 mL
Collection Container:
Lavender K2EDTA Tube or Light Green Lithium Heparin Plasma Separator Tube (PST)
Transport Temperature:
Frozen
Additional Information:
Separate plasma from cells and transfer into a standard aliquot tube.
Changes to Reference Ranges
Allergen, Food, Alpha-Gal IgE (GALIGE)
Less than 0.10:
No significant level detected (Class Score 0)
0.10-0.34:
Clinical relevance undetermined (Class Score 0/1)
0.35-0.70:
Low (Class Score 1)
0.71-3.50:
Moderate (Class Score 2)
3.51-17.50:
High (Class Score 3)
17.51-50.00:
Very high (Class Score 4)
50.01-100.00:
Very high (Class Score 5)
Greater than 100.00:
Very high (Class Score 6)
IBD Serology Disease Panel (IBDSER)
Saccharomyces cerevisiae Antibody, IgA
20.0 Units or less:
Negative
20.1-24.9 Units:
Equivocal
25.0 Units or greater:
Positive
Saccharomyces cerevisiae Antibody, IgG
20.0 Units or less:
Negative
20.1-24.9 Units:
Equivocal
25.0 Units or greater:
Positive
ANCA IFA Titer
Less than 1:20
ANCA IFA Pattern
None detected
Macroprolactin (MACPRO)
Prolactin
Male
2.1-17.7 ng/mL
Female, 1-9 years
2.1-17.7 ng/mL
Female, 10 years and older
2.8-29.2 ng/mL
Monomeric, Prolactin
Male
2.1-13.3 ng/mL
Female, 1-9 years
2.1-13.3 ng/mL
Female, 10 years and older
2.8-19.5 ng/mL
Percent
Greater than 50%
Prolactin, Dilution Study (PROLM)
Prolactin
Male
2.1-17.7 ng/mL
Nonpregnant Female, 1-9 years
2.1-17.7 ng/mL
Nonpregnant Female, 10 years and older
2.8-29.2 ng/mL
Nicotine & Metabolites, Urine (UNICOT)
Nicotine
15 ng/mL
Cotinine (metabolite)
15 ng/mL
3-OH-Cotinine (metabolite)
50 ng/mL
Anabasine (tobacco biomarker)
5 ng/mL
Changes to Test Build
Allergen, Food, Alpha-Gal IgE (GALIGE)
Components Affected
Allergen, Food, Alpha-Gal IgE
Reflex: Allergen Interp, Immunocap Score IgE
IBD Serology Disease Panel (IBDSER)
Components Affected
S. cerevisiae Antibody, IgA
S. cerevisiae Antibody, IgG
Inflammatory Bowel Disease Interp
ANCA IFA Titer
ANCA IFA Pattern
EER Inflammatory Bowel Diseases
Nicotine & Metabolites, Urine (UNICOT)
Components Affected
Remove Nornicotine, Urine
Test Discontinuations
HIV-1 Genotype (HIVGEN)
Reason for Discontinuation:
No longer offered by the vendor
Alternative Test:
HIV 1 Drug Resistance by Next Generation Sequencing (HIVNGS)
Anti-Neut Cyto Ab with Reflex to Titer and MPO/PR3 Ab (NCYTO)
Reason for Discontinuation:
No longer offered by the vendor
Alternative Test:
Neutrophil Cytoplasmic Antibody (ANCA)
Any additional information will be included in a future Technical Update. If you have any questions about these changes, please contact Client Services for assistance.