Special Communication
Test Menu Optimization & Discontinuations: MGLESE, MYSGRV, & PARSYN
Cleveland Clinic regularly updates its clinical practices to align with the latest testing practices as a part of our Continuous Improvement efforts.
A recent review has identified tests that will be discontinued in favor of more simple, focused, and cost-effective testing options.
Please refer to the test information below or contact Client Services for assistance.
Test Discontinuations
Effective August 3, 2021.
Myasthenia Gravis (MG)/Lambert-Eaton Syndrome (LES) Evaluation, Serum (MGLESE)
Alternative Tests:
Acetylcholine Receptor Binding Antibody Test (ACHRAB)*
ACHRAB Clinical Info:
Anti-acetylcholine receptor binding antibody test is used as an aid in the diagnosis of myasthenia gravis. A negative result cannot exclude myasthenia gravis. Clinical correlation is required.
*Note: Acetylcholine Receptor Modulating Antibody (ACEMOD) and Muscle-Specific Kinase Antibody (MUSK) can be ordered separately if clinically indicated.
P/Q-Type Voltage-Gated Calcium Channel (VGCC) Antibody Test (VOLTCA)
VOLTCA Clinical Info:
Aids in the evaluation of muscle weakness in the context of neuromuscular junction disorder with or without cancer, or the diagnosis of paraneoplastic neurological syndromes.
Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum (MYSGRV)
Alternative Tests:
Acetylcholine Receptor Binding Antibody Test (ACHRAB)*
ACHRAB Clinical Info:
Anti-acetylcholine receptor binding antibody test is used as an aid in the diagnosis of myasthenia gravis. A negative result cannot exclude myasthenia gravis. Clinical correlation is required.
*Note: Acetylcholine Receptor Modulating Antibody (ACEMOD) and Muscle-Specific Kinase Antibody (MUSK) can be ordered separately if clinically indicated.
Paraneoplastic Syndrome Ab Panel with Reflex (PARSYN)
Alternative Tests:
Paraneoplastic Autoantibody Evaluation, Serum (PARNEO)
PARNEO Clinical Info:
This supplemental testing is recommended in cases of chorea, vision loss, cranial neuropathy, and myelopathy.